The refractory horse was eliminated from the race when he refused to obey the jockey.
This response lasts for about 10 minutes, after which the cat becomes refractory to catnip's effects for roughly 30 minutes.
Now, beyond any reasonable doubt, our presidential aspirants are created by an openly shabby process, one that is intentionally refractory to both intelligence and virtue.
From a purely practical perspective, there is also value in a refractory period the mind needs time to rest and assimilate the academic years content.
This approach has shown to be promising in cancers refractory to other conventional treatments.